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Mecanismes Moleculars de Neurodegeneració

Mitochondrial DNA deletions in cerebrospinal fluid of patients with idiopathic REM sleep behavior disorder.

uigròs M, Calderon A, Martín-Ruiz D, Serradell M, Fernández M, Muñoz-Lopetegi A, Mayà G, Santamaria J, Gaig C, Colell A, Tolosa E, Iranzo A, Trullas R,
2024

Quantification of rare somatic single nucleotide variants by droplet digital PCR using SuperSelective primers.

Pablo-Fontecha V, Hernández-Illán E, Reparaz A, Asensio E, Morata J, Tonda R, Lahoz S, Parra C, Lozano JJ, García-Heredia A, Martínez-Roca A, Beltran S, Balaguer F, Jover R, Castells A, Trullàs R, Podlesniy P, Camps J.,
2023

Molecular basis for maternal inheritance of human mitochondrial DNA

Lee W, Zamudio-Ochoa A, Buchel G, Podlesniy P, Marti Gutierrez N, Puigròs M, Calderon A, Tang HY, Li L, Mikhalchenko A, Koski A, Trullas R, Mitalipov S, Temiakov D,
2023

Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis

de Dios, C., Abadin, X., Roca-Agujetas, V., Jimenez-Martinez, M., Morales, A., Trullas, R., Mari, M., Colell, A.,,
2023

Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene

Ortega, M., De Toma, I., Fernández-Blanco, Á., Calderón, A., Barahona, L., Trullàs, R., Sabidó, E., Dierssen, M,
2022

Cell-free mitochondrial DNA deletions in idiopathic, but not LRRK2, Parkinson’s disease

Puigròs M, Calderon A, Pérez-Soriano A, de Dios C, Fernandez M, Colell A, Martí MJ, Tolosa E, Trullas R,
2022

Ca2+-modulated photoactivatable imaging reveals neuron-astrocyte glutamatergic circuitries within the nucleus accumbens.

Serra I, Esparza J, Delgado L, Martín-Monteagudo C, Puigròs M, Podlesniy P, Trullás R, Navarrete M,
2022

Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease

Roca-Agujetas V, Barbero-Camps E, de Dios C, Podlesniy P, Abadin X, Morales A, Marí M, Trullàs R, Colell A.,
2021

NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3

Parcerisas A, Pujadas L, Ortega-Gascó A, Perelló-Amorós B, Viais R, Hino K, Figueiro-Silva J, La Torre A, Trullás R, Simó S, Lüders J, Soriano E.,
2020

"Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres

Salmina K, Bojko A, Inashkina I, Staniak K, Dudkowska M, Podlesniy P, Rumnieks F, Vainshelbaum NM, Pjanova D, Sikora E, Erenpreisa J.,
2020

Accumulation of Mitochondrial 7S DNA in Idiopathic and LRRK2 Associated Parkinson's Disease

Podlesniy P, Puigròs M, Serra N, Fernández-Santiago R, Ezquerra M, Tolosa E, Trullas R.,
2019

''NEURONAL PENTRAXIN 1 NEGATIVELY REGULATES EXCITATORY SYNAPSE DENSITY AND SYNAPTIC PLASTICITY.''

FIGUEIRO-SILVA J, GRUART A, CLAYTON KB, PODLESNIY P, ABAD MA, GASULL X, DELGADO-GARCÍA JM, TRULLAS R.,
2015

''URIDINE 5'-TRIPHOSPHATE PROMOTES IN VITRO SCHWANNOMA CELL MIGRATION THROUGH MATRIX METALLOPROTEINASE-2 ACTIVATION.''

LAMARCA A, GELLA A, MARTIAÑEZ T, SEGURA M, FIGUEIRO-SILVA J, GRIJOTA-MARTINEZ C, TRULLAS R, CASALS N,
2014

''LOW CSF CONCENTRATION OF MITOCHONDRIAL DNA IN PRECLINICAL ALZHEIMER'S DISEASE''

PODLESNIY P, FIGUEIRO-SILVA J, LLADO A, ANTONELL A, SANCHEZ-VALLE R, ALCOLEA D, LLEO A, MOLINUEVO JL, SERRA N, TRULLAS R.,
2013

''ALLEVIATION OF NEUROPATHIC PAIN HYPERSENSITIVITY BY INHIBITING NEURONAL PENTRAXIN 1 IN THE ROSTRAL VENTROMEDIAL MEDULLA.''

ZAPATA A, PONTIS S, SCHEPERS RJ, WANG R, OH E, STEIN A, BÄCKMAN CM, WORLEY P, ENGUITA M, ABAD MA, TRULLAS R, SHIPPENBERG TS.,
2012

''HIF-1ALFA; IS NEUROPROTECTIVE DURING THE EARLY PHASES OF MILD HYPOXIA IN RAT CORTICAL NEURONS.''

LÓPEZ-HERNÁNDEZ B, POSADAS I, PODLESNIY P, ABAD MA, TRULLAS R, CEÑA V.,
2012

''NP1 REGULATES NEURONAL ACTIVITY-DEPENDENT ACCUMULATION OF BAX IN MITOCHONDRIA AND MITOCHONDRIAL DYNAMICS.''

CLAYTON KB, PODLESNIY P, FIGUEIRO-SILVA J, LÓPEZ-DOMÉNECH G, BENITEZ L, ENGUITA M, ABAD MA, SORIANO E, TRULLAS R.,
2012

''THE EUTHERIAN ARMCX GENES REGULATE MITOCHONDRIAL TRAFFICKING IN NEURONS AND INTERACT WITH MIRO AND TRAK2.''

LÓPEZ-DOMÉNECH G, SERRAT R, MIRRA S, D'ANIELLO S, SOMORJAI I, ABAD A, VITUREIRA N, GARCÍA-ARUMÍ E, ALONSO MT, RODRIGUEZ-PRADOS M, BURGAYA F, ANDREU AL, GARCÍA-SANCHO J, TRULLAS R, GARCIA-FERNÀNDEZ J, SORIANO E.,
2012

"AMYLOID BETA OLIGOMERS INDUCE CA2+ DYSREGULATION AND NEURONAL DEATH THROUGH ACTIVATION OF IONOTROPIC GLUTAMATE RECEPTORS."

ALBERDI E, SÁNCHEZ-GÓMEZ MV, CAVALIERE F, PÉREZ-SAMARTÍN A, ZUGAZA JL, TRULLAS R, DOMERCQ M, MATUTE C.,
2010

"ASSOCIATIVE LEARNING AND CA3-CA1 SYNAPTIC PLASTICITY ARE IMPAIRED IN D1R NULL, DRD1A-/- MICE AND IN HIPPOCAMPAL SIRNA SILENCED DRD1A MICE."

ORTIZ O, DELGADO-GARCÍA JM, ESPADAS I, BAHÍ A, TRULLAS R, DREYER JL, GRUART A, MORATALLA R.,
2010

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