Publications

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José Carlos Fernández-Checa

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Klionsky DJ;Abdel-Aziz AK;Abdelfatah S;Abdellatif M;Sanchez-Alcazar JA;Arevalo M.A.;Alonso A.;Beltran J.S.D.O;Boya P.;Casas J.;Collel A.;Coll N.S.;Crespo J.L.;Cuadrado A.;Duran R.V.;Escalante R.;Fernandez-Checa J.C.;Figueras;Moles A.;Perez-Perez M.E.;Sanz,
2021

Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]

Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal GP, Lucena MI, Andrade RJ, Fromenty B, Kranendonk M, Cubero FJ, Nelson LJ.,
2021

Dietary and Genetic Cholesterol Loading Rather Than Steatosis Promotes Liver Tumorigenesis and NASH-Driven HCC

Ribas V, de la Rosa LC, Robles D, Núñez S, Segalés P, Insausti-Urkia N, Solsona-Vilarrasa E, Fernández-Checa JC, García-Ruiz C. ,
2021

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

Torres S, Solsona-Vilarrasa E, Nuñez S, Matías N, Insausti-Urkia N, Castro F, Casasempere M, Fabriás G, Casas J, Enrich C, Fernández-Checa JC, Garcia-Ruiz C. Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disea,
2021

STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway

Conde de la Rosa L, Garcia-Ruiz C, Vallejo C, Baulies A, Nuñez S, Monte MJ, Marin JJG, Baila-Rueda L, Cenarro A, Civeira F, Fuster J, Garcia-Valdecasas JC, Ferrer J, Karin M, Ribas V, Fernandez-Checa JC.,
2021

GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cells

Hernandez S, Simoni-Nieves A, Gerardo-Ramírez M, Torres S, Fucho R, Gonzalez J, Castellanos-Tapia L, Hernández-Pando R, Tejero-Barrera E, Bucio L, Souza V, Miranda-Labra R, Fernández-Checa JC, Marquardt JU, Gomez-Quiroz LE, García-Ruiz C, Gutiérrez-Ruiz M,
2021

Sphingomyelinases and Liver Diseases

Insausti-Urkia N, Solsona-Vilarrasa E, Garcia-Ruiz C, Fernandez-Checa JC.,
2020

Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.

Eun Hee Koh;Ji Eun Yoon;Myoung Seok Ko;Jaechan Leem;Ji-Young Yun;Chung Hwan Hong;Yun Kyung Cho;Seung Eun Lee;Jung Eun Jang;Ji Yeon Baek Hyun Ju Yoo;Su Jung Kim;Chang Ohk Sung;Joon Seo Lim;Won-Il Jeong;Sung Hoon Back;In-Jeoung Baek;Sandra Torres;Estel Sols,
2020

MITOCHONDRIAL CHOLESTEROL AND CANCER

Garcia-Ruiz C, de la Rosa LC, Ribas V, Fernandez-Checa JC.,
2020

Cholesterol Induces Nrf-2- And HIF-1 α-Dependent Hepatocyte Proliferation and Liver Regeneration to Ameliorate Bile Acid Toxicity in Mouse Models of NASH and Fibrosis

Kaminsky-Kolesnikov Y, Rauchbach E, Abu-Halaka D, Hahn M, García-Ruiz C, Fernandez-Checa JC, Madar Z, Tirosh O.,
2020

Editorial: Autophagy and Related Transcription Factors in Liver and Gut Diseases

Eid N, Menon MB, Thomes P, Zeng T, Raimundo N, Fernandez-Checa JC, Wang L, Ito Y, Otsuki Y, Adeghate E.,
2020

Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure

Torres S, Baulies A, Insausti-Urkia N, Alarcón-Vila C, Fucho R, Solsona-Vilarrasa E, Núñez S, Robles D, Ribas V, Wakefield L, Grompe M, Lucena MI, Andrade RJ, Win S, Aung TA, Kaplowitz N, García-Ruiz C, Fernández-Checa JC.,
2019

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes.

Solsona-Vilarrasa E, Fucho R, Torres S, Nuñez S, Nuño-Lámbarri N, Enrich C, García-Ruiz C, Fernández-Checa JC.,
2019

The Effect of Zinc Acexamate on Oxidative Stress, Inflammation and Mitochondria Induced Apoptosis in Rat Model of Renal Warm Ischemia

Hadj Abdallah N, Baulies A, Bouhlel A, Bejaoui M, Zaouali MA, Ben Mimouna S, Messaoudi I, Fernandez-Checa JC, García Ruiz C, Ben Abdennebi H.,
2018

The 2-oxoglutarate Carrier Promotes Liver Cancer by Sustaining Mitochondrial GSH Despite Cholesterol Loading

Baulies A, Montero J, Matías N, Insausti N, Terrones O, Basañez G, Vallejo C, Conde de La Rosa L, Martinez L, Robles D, Morales A, Abian J, Carrascal M, Machida K, Kumar DBU, Tsukamoto H, Kaplowitz N, Garcia-Ruiz C, Fernández-Checa JC.,
2018

Antiapoptotic BCL-2 Proteins Determine sorafenib/regorafenib Resistance and BH3-mimetic Efficacy in Hepatocellular Carcinoma

Tutusaus A, Stefanovic M, Boix L, Cucarull B, Zamora A, Blasco L, de Frutos PG, Reig M, Fernandez-Checa JC, Marí M, Colell A, Bruix J, Morales A.,
2018

Mitochondria, cholesterol and cancer cell metabolism

Ribas V, Garcia-Ruiz C, Fernandez-checa JC,
2016

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