Deficient p27 phosphorylation at serine 10 increases macrophague foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.

The Department investigates the molecular basis and signaling pathways associated with damage and repair in ischemic and inflammatory-based diseases associated with abdominal organs (liver, pancreas, and kidney), cancer, and cardiovascular disease but also other. idiopathic diseases such as pulmonary fibrosis.