Interferon stimulated gene 15 pathway is a novel mediator of endothelial dysfunction and aneurysms development in angiotensin II infused mice through increased oxidative stress.

The Department investigates the molecular basis and signaling pathways associated with damage and repair in ischemic and inflammatory-based diseases associated with abdominal organs (liver, pancreas, and kidney), cancer, and cardiovascular disease but also other. idiopathic diseases such as pulmonary fibrosis.