Matrix metalloproteinase-10 (MMP-10) is up-regulated by thrombin in endothelial cells and increases in patients with increased thrombin generation.
The Department investigates the molecular basis and signaling pathways associated with damage and repair in ischemic and inflammatory-based diseases associated with abdominal organs (liver, pancreas, and kidney), cancer, and cardiovascular disease but also other. idiopathic diseases such as pulmonary fibrosis.