Parkinson's disease is the second most common neurodegenerative disease after Alzheimer’s disease and is characterized by a progressive loss of neurons involved in the control of movement.
Parkinson's disease is the second most common neurodegenerative disease after Alzheimer’s disease and is characterized by a progressive loss of neurons involved in the control of movement.
The oligonucleotide, designed to act only on dopaminergic and noradrenergic neurons, reduces the production and accumulation of the mutant alpha-synuclein protein, a key protein in the development of Parkinson's disease
The work is led by the Barcelona Biomedical Research Institute of the CSIC and IDIBAPS
The study recently published in Molecular Neurodegeneration journal with Vicente Roca as the first author and directed by
They have participated in the 4th edition of an international consensus on the interpretation, mechanisms and various multidisciplinary aspects of autophagy.
An international team of multidisciplinary researchers has identified one of the molecular mechanisms underlying cardiac alternans, an alteration of the heart rhythm that facilitates the induction of ventricular fibrillation, a potentially fatal arrhythmia. Furthermore, they show that people with loss of ryanodine receptor (RyR) function are prone to induction of ventricular fibrillation and sudden death caused by cardiac alternans.
The importance of including women in all sciences at all levels